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Bi/CNS 150
Profs:

Ralph Adolphs
Mary Kennedy
Henry Lester

Neuroscience

Caltech
Fall 2009

 

Catalog Description

Bi/CNS 150. Neurobiology. 10 units (4-0-6); first term. General principles of the function and organization of nervous systems, providing both an overview of the subject and a foundation for advanced courses. Topics include the physical and chemical bases for action potentials, synaptic transmission, and sensory transduction; anatomy; development; sensory and motor pathways; memory and learning at the molecular, cellular, and systems level; and the neuroscience of brain diseases. Instructors: Adolphs, Kennedy, Lester.

Lectures will be held at MWF 11-12 in the 1st Floor Broad Center Lecture Hall

 


News

11/17/09

Problem set 5 posted

11/13/09

Midterm grade distributions posted

11/13/09

Midterm answer key posted

11/10/09

Problem Set 4 posted

10/28/09

Midterm posted; PS 1-3 Answer Keys Posted

10/23/09

Link to webcasts: Bi150 lecture webcasts

10/20/09

Problem Set 3 Posted

10/13/09

Problem Set 2 Posted

10/06/09

Problem Set 1 Posted

9/30/09

Welcome to Bi/CNS 150!

9/30/09

Problem Set 0 Posted


Contacts

Contact information for the following people is on the Instructors & Recitation Sections page.

For questions about specific recitation sections, email the section TA.
For issues with the website, email Sindhu.

Link to webcasts: Bi150 2009 Webcasts

 


Course Calendar & Links

Please refresh your browser to make sure you are seeing the most recent version of this page.
Lecture images are often posted in draft form the evening preceding the lecture, by 9 PM.

Monday

Tuesday

Wednesday

Thursday

Friday

September 29

September 29

September 30

October 1

October 2

 

 

Introduction to the course. Membrane structure. Deriving the ionic behavior of the nervous system from first principles. Nernst potentials. The major proteins of membrane physiology.
(Lester)

Molecular Biology Boot Session

Broad 8-9 PM

(Lester)

Voltage-dependent channels and action potentials. Part I
(Lester)

 

 

Chapters 6-9

 

Chapters 6-9

October 5

October 6

October 7`

October 8

October 9

Voltage-dependent channels and action potentials. Part II
(Lester)

Electrophysiology Boot Session

Broad 8-9 PM

(Lester)

Synapses, Part I: Presynaptic Transmitter release

(Lester)

Discussion Section

Synapses, Part II: The acetylcholine receptor and organization of the neuromuscular junction
(Lester)

Chapters 6-9

Problem Set 1

Chapters 14 & 15

 

Chapter 11

October 12

October 13

October 14

October 15

October 16

Inhibition; electrical integration of signals; cable properties of dendrites and and axons
(Lester)

 Problem Set 1 Due at 4:30 PM

Dendritic excitability, Inward rectifiers, Glia
(Lester)

Discussion Section

AMPA receptors and GABA receptors: organization of CNS synapses
(Kennedy)

Chapters 2 & 12

Problem Set 2

 

Chapters 12

October 19

October 20

October 21

October 22

October 23

Synaptic Plasticity; LTP and LTD
(Kennedy)

Problem Set 2 Due at 4:30 PM

NMDA Receptors; the biochemistry of synaptic plasticity
(Kennedy)

Discussion Section

The G protein pathway in neuroscience
(Lester)

Chapters 13 & 63

Problem Set 3

Chapters 12 & 63

Chapter 13

October 26

October 27

October 28

October 29

October 30

Development of the Nervous system #1
(Lester)

Problem Set 3 Due at 4:30 PM

Development of the Nervous system #2
(Lester)

MIDTERM

No Discussion Section

Anatomy of the CNS
(Adolphs)

Chapters 52 through 56

 

Chapters 52 through 56

Chapters 17, 18, first half of 19

November 2

November 3

November 4

November 5

November 6

Vision; the retina and detection of light
(Lester)

 

MIDTERM DUE at 4:30 PM

The Visual System From retina to visual cortex
(Adolphs)

Discussion Section

Visual System; cortical processing and object recognition
(Adolphs)
Hubel & Wiesel video
Optic ataxia video

Chapter 26

Chapters 21 & 27

 

Chapter 25

November 9

November 10

November 11

November 12

November 13

The auditory system
(Adolphs)

 

The Somatosensory System
(Adolphs)

Discussion Section

The Olfactory System
(Lester)

Chapter 30

Problem Set 4

Chapter 22

 

Chapter 32

November 16

November 17

November 18

November 19

November 20

The motor system
(Adolphs)

Problem Set 4 Due at 4:30 PM

Learning and Memory I Types of Memory; non-declarative memory
(Adolphs)

Discussion Section

Learning and Memory II Declarative Memory and modulation of memory
(Adolphs)

Chapters 38, 42 & 43

Problem Set 5

Chapter 62

 

Chapter 62

November 23

November 24

November 25

November 26

November 27

Aminergic Systems, Mood and Depression
(Kennedy)

Problem Set 5 Due at 4:30 PM

Emotion and Social Behavior
(Adolphs)

 

THANKSGIVING HOLIDAY

Chapter 61

Problem Set 6

Chapters 49 & 50

 

 

November 30

December 1

December 2

December 3

December 4

Schizophrenia
(Lester)

Problem Set 6 Due at 4:30 PM

Neurodegenerative Disorders Alzheimer's disease

And

Parkinson’s Disease
(Lester)

 

Current Resarch in Neuroscience

(Kennedy, Lester, Adolphs)

Chapter 60

 

Chapter 58

 

Final Exam


DUE December 11 at 5:00 PM